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J Controlled Release 2026 · DNA-directed multivalent LNP for T cell · Kelly/Kamat

"Lipid nanoparticles (LNPs) are a powerful emerging tool for in vivo T cell engineering to treat diseases ranging from B cell lymphomas and other cancers to autoimmune diseases. Key challenges in designing these therapeutics include achieving both precise cell targeting and effi…

Type
paper
Domain
oncology
Grade
conference
License
LIGHT_HOPE_proprietary
Provenance
m622_verify_wave_3_2026-05-16
evidence_grade
A
category
lnp_t_cell_targeting_platform
status
verified
instance_tag
sunvax-antibody-2025
clinical_claim_softening
"preclinical LNP design study · not human clinical · not intended to guide individual patient treatment choices"
journal
Journal of Controlled Release
year
2026
authors
Mary D Kelly,Neha P Kamat
abstract_snippet
"Lipid nanoparticles (LNPs) are a powerful emerging tool for in vivo T cell engineering to treat diseases ranging from B cell lymphomas and other cancers to autoimmune diseases. Key challenges in designing these therapeutics include achieving both precise cell targeting and ef
pmid
41916505
doi
10.1016/j.jconrel.2026.114885
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