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JCO 2026 · Phase II BCMA CAR-T in NDMM (CAREMM-001) · ex vivo baseline

"Patients with newly diagnosed multiple myeloma (NDMM) who are ineligible for or not proceeding to autologous stem-cell transplantation (ASCT)—often because of age or frailty—have limited opportunities to receive multiple effective lines of therapy, underscoring the need for nov…

Type
paper
Domain
oncology
Grade
conference
License
LIGHT_HOPE_proprietary
Provenance
m622_intel_seed_2026-05-16
evidence_grade
A
category
ex_vivo_car_t_comparison
status
verified
instance_tag
sunvax-antibody-2025
clinical_claim_softening
"Phase II ex vivo BCMA CAR-T data · NOT directly comparable to ESO-T01 in vivo CAR-T safety/efficacy yet · cross-modality reference baseline only"
journal
Journal of Clinical Oncology
year
2026
authors
Wenqiang Yan,Gang An
abstract_snippet
"Patients with newly diagnosed multiple myeloma (NDMM) who are ineligible for or not proceeding to autologous stem-cell transplantation (ASCT)—often because of age or frailty—have limited opportunities to receive multiple effective lines of therapy, underscoring the need for
pmid
41759038
doi
10.1200/JCO-25-01969
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