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Exp Hematol Oncol 2025 · Review: In vivo CAR-T cell engineering · concept, progress, challenges

"Chimeric antigen receptor (CAR)-T therapy has evolved into a transformative immunotherapy approach with expanding applications across cancer, autoimmune disorders, and other disease areas · in vivo CAR-T therapy has been proposed: the in vivo or in situ programming of CAR-T cel…

Type
paper
Domain
oncology
Grade
conference
License
LIGHT_HOPE_proprietary
Provenance
m622_intel_seed_2026-05-16
evidence_grade
A
category
in_vivo_car_t_review
status
verified
instance_tag
sunvax-antibody-2025
clinical_claim_softening
"review · NOT primary clinical data"
journal
Experimental Hematology & Oncology
year
2025
authors
Yizhao Chen,Ruilin Li
abstract_snippet
"Chimeric antigen receptor (CAR)-T therapy has evolved into a transformative immunotherapy approach with expanding applications across cancer, autoimmune disorders, and other disease areas · in vivo CAR-T therapy has been proposed: the in vivo or in situ programming of CAR-T
pmid
41250215
doi
10.1186/s40164-025-00725-5
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