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Bone Marrow Transplant 2026 · Bridging therapy before anti-BCMA CAR-T · Rasche/Raab

"Use of anti-B-cell maturation antigen (BCMA) chimeric antigen receptor T-cell (CAR-T) therapy to treat relapsed/refractory multiple myeloma is increasing. Studies suggest that effective bridging therapy (BT) prior to anti-BCMA CAR-T therapy can enhance efficacy and safety outco…

Type
paper
Domain
oncology
Grade
conference
License
LIGHT_HOPE_proprietary
Provenance
m622_verify_wave_2_2026-05-16
evidence_grade
A
category
bcma_car_t_clinical_workflow
status
verified
instance_tag
sunvax-antibody-2025
clinical_claim_softening
"expert panel consensus · ex vivo BCMA CAR-T workflow context · not intended to guide individual patient treatment choices · in vivo BCMA CAR-T (ESO-T01 etc) sits separately"
journal
Bone Marrow Transplantation
year
2026
authors
Leo Rasche,Marc S Raab
abstract_snippet
"Use of anti-B-cell maturation antigen (BCMA) chimeric antigen receptor T-cell (CAR-T) therapy to treat relapsed/refractory multiple myeloma is increasing. Studies suggest that effective bridging therapy (BT) prior to anti-BCMA CAR-T therapy can enhance efficacy and safety out
pmid
42129310
doi
10.1038/s41409-026-02905-1
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