Conference LibraryGated
ACS Nano 2026 · Spleen-Tropic LNP for in vivo CAR-T engineering · Guo/Li
"The delivery of nucleic acids via lipid nanoparticles (LNPs) to generate chimeric antigen receptor (CAR) T cells in vivo represents a promising therapeutic strategy for a broad spectrum of diseases. Nevertheless, the low efficiency of in vivo gene delivery to T cells remains a …
- Type
- paper
- Domain
- oncology
- Grade
- conference
- License
- LIGHT_HOPE_proprietary
- Provenance
- m622_verify_wave_2_2026-05-16
- evidence_grade
- A
- category
- in_vivo_car_t_lnp_platform
- status
- verified
- instance_tag
- sunvax-antibody-2025
- clinical_claim_softening
- "preclinical animal model · NOT human clinical data · not intended to guide individual patient treatment choices"
- journal
- ACS Nano
- year
- 2026
- authors
- Qiang Guo,Jinghong Li
- abstract_snippet
- "The delivery of nucleic acids via lipid nanoparticles (LNPs) to generate chimeric antigen receptor (CAR) T cells in vivo represents a promising therapeutic strategy for a broad spectrum of diseases. Nevertheless, the low efficiency of in vivo gene delivery to T cells remains
- pmid
- 42130331
- doi
- 10.1021/acsnano.6c00706
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