'Younger-for-Longer' (Healthspan) vs 'Live-Longer' (Lifespan) Framing in 2026 Geroscience: Healthspan as Primary Translational Endpoint

Major geroscience consensus is shifting toward healthspan — years free of major chronic disease and functional disability — as the primary translational endpoint rather than chronological lifespan extension. This framing shift carries methodological implications for trial design

Type

evidence-claim

Domain

methodology

Grade

B

License

CC BY-NC 4.0

card_id

L-027

hallmarks

cluster

methodology

primary_disease_area

longevity_general

evidence_tier

B

evidence_anchor_count

5

intake_round

R23

intake_date

2026-05-26

related_experts

related_biomarkers

related_interventions

related_trials

collection_pages

/research/methodology/healthspan-vs-lifespan,/research/foundations/geroscience-framework

LongProof Longevity Dynamic · LIGHT HOPE / x1000.ai · longevity.x1000.ai · 2026 · source

Read-only aggregated view. Longevity Evidence is the source of record; this catalog shows provenance as-is — no ratings, no reviews.